šŸŒ A CRISPR WORLD

THE GENE EDITING tool CRISPR is transforming medicine. But will it have an even larger impact on our planet?

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DEEPFATEĀ šŸŒ AĀ CRISPR WORLD

The gene editing tool CRISPRĀ is transforming medicine. But will it have an even larger impact on our planet?

Scientist analyze the soil microbes responsible for emitting and storing carbon (Innovative Genomics Institute)

HEARD OF CRISPR?

  • As I've previously written, it's a pretty mind boggling medical invention:

  • Imagine being able to "highlight" and then "delete" sections of DNA, in real time.

  • It's commonly called a "gene editor," but CRISPR's actually a segment of DNA that can detect and destroy other DNA.

  • Sidebar: CRISPR's origin story is also fantastic. It was discovered by an all-female team of doctors, who later won the Nobel Prize.

CRISPR HAS SOME incredible real world applications.

  • They include curing genetic diseases, and revolutionizing pediatric cancer treatments.

  • But more and more scientists are now using CRISPR to optimize our food supply.

SLICKER COWS. MORE nutritious tomatoes.Ā 

  • One edit, approved by the US Food and Drug Administration, gives cows a slick coat to help them tolerate increasing temperatures.

  • A more nutritious, CRISPR-edited tomato is on sale in Japan.

  • Fertilizer and pesticide firms are also on notice:

  • All sorts of plants could be made more resistant to common pathogens and pests.

  • And scientists are even engineering crops with drought tolerance.

  • Higher yields, with less fertilizer and pesticides, while consuming less water: it sounds too good to be true.

BUT WHAT'S COMING next could help slow our warming planet, benefittingĀ billions.

  • Scientists are editing the genetic code of gut bacteria in order to reduce the amount of greenhouse gases emitted by farm animal digestion.

  • They're also altering the genes of plant and soil microbes, to let them capture and store more carbon in soil.

  • It's estimated that 1/2 of the Earth's habitable land is used for agriculture in some way shape or form.

  • The world's wheat, corn, and rice crops could soon start absorbing and storing its carbon.

THIS WAS NOT the intended use case. Good.

  • Check out the progression over the past decade: it's a remarkable reminder of how new tech can be used in unexpected ways.

  • CRISPR was originally considered a novel way to treat diseases, especially rare and incurable ones, and it very much still is.

  • But by putting CRISPR to work editing plant and microbe genomes, the technology could end up benefitting billions ā€”not just the very sickā€” through higher yielding crops, and by reducing, capturing and storing the world's carbon output.

  • Itā€™s a great reminder of how incredible medical science is. But there's a business lesson hidden in here for all of us, too.

  • Can the exact same tech or systems that you already use in your day-to-day be applied to new problems in order to benefit a far, far larger audience?

Engineering drought tolerance in plants through CRISPR / Cas genome editing >>>

CRISPR wants to feed the world >>>

In 10 years, CRISPR transformed medicine. Can it now help us deal with climate change? >>>

Can we hack DNA in plants to fight climate change? >>>

Written by Jon Kallus. Any feedback? Simply reply.Ā Thank you for reading.

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